Testosterone antiaging, fashion or health risk?

From the United States to Europe, the use of testosterone is growing as an alleged elixir of youth. But between social promises and science, experts invite caution.

The Antiaging testosterone It has become one of the most discussed trends in the world of well-being. Give it United states anEurope The number of men and women who take the hormone is growing outside the clinical indications, driven by the promise of more energy, physical strength and youth. But what does science really say?

In the United States, the debate has exploded in recent years. In December 2025 a panel of experts from the Food and Drug Administration has reopened the discussion on testosterone replacement therapy, evaluating a possible loosening of restrictions. At the same time, the unapproved use of testosterone has increased, especially among young men who take it to improve muscle mass and physical performance.

Social media and longevity clinics

Antiaging testosterone is aggressively promoted on social networks and in some wellness clinics, which present it as a key to slowing down aging. However, the FDA itself made it clear in March 2025 that testosterone benefits and safety have not been proven to counteract the natural age-related hormonal decline. Despite this, boosters, supplements and devices for self-measurement of hormone levels proliferate on the web.

Women also look at testosterone

The phenomenon also affects the female audience. In the United States, many women ask for information on anti-aging testosterone, despite the fact that there are no approved products for women. According to experts, expectations are often fueled by influencers and misleading messages. “It is not an anti-aging drug”, reiterate numerous specialists.

Testosterone is present in both men and women and performs important functions on bones, muscles, mood and libido. With age, levels decrease, but international guidelines indicate therapy only in case of documented deficiency and clinical symptoms.

The opinion of the Italian experts

Second Rossella Nappi, gynecologist and endocrinologist, there is no evidence that testosterone improves disorders such as cognitive fog or mood changes in menopause. The only indication recognized in women concerns the disorder of hypoactive sexual desire, with very controlled dosages. Also Joseph Cirino, pharmacologist, points out that the improvements observed in some studies may be related to the placebo effect.

Risks and Limits of Anti-Aging Testosterone

Improper use of testosterone can result in side effects. In women, excessive dosages can cause acne, increased hair and hair loss. In men, on the other hand, testosterone can improve sexual desire if prescribed correctly, but it does not act as a universal elixir. Energy and well-being depend on many factors, including psychological ones.

When therapy is really useful

Second Daniele Gianfrilli, endocrinologist andrologist, replacement therapy is indicated only in the presence of diagnosed hypogonadism. In these cases it can improve not only the sexual sphere, but also some aspects of general health. At the moment, however, there is no evidence of efficacy and safety of testosterone as an anti-aging treatment for healthy people.

prudence first of all

The success of anti-aging testosterone tells the widespread desire to counteract the passing of time. But experts agree on one point: without medical diagnosis and without scientific evidence, the use of the hormone as an anti-aging remains a risky bet. Science calls for caution, far from the easy promises of marketing.